Efficacy of Active Carbon towards the Absorption of Deoxynivalenol in Pigs

Published on: 04/27/2015
Author/s : Mathias Devreese,1,* Gunther Antonissen,1,2 Patrick De Backer,1 and Siska Croubels1 Annie Pfohl-Leszkowicz, External Editor (1Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, 2 Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University)

Toxins (Basel). 2014 Oct; 6(10): 2998–3004.Published online 2014 Oct 21. doi: 10.3390/toxins6102998Copyright © 2014 by the authors; licensee MDPI, Basel, Switzerland.This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).AbstractIn order to assess the in vivo efficacy of ...

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Fernando Tamames Fernando Tamames
Executive
Special Nutrients Special Nutrients
Miami, Florida, United States
April 27, 2015

Excellent study to see the punctual effect (one dose one treatment) on activated charcoal (AC) as an emergency treatment (antidote) for poisoning and drug overdose in this case of DON.

This study is specially valuable since the pig gastro intestinal system is similar to humans where AC is used as a punctual emergency treatment (one dose one treatment) and it is not recommended to be used on a continual basis due to is side effects.

AC has been known to be an effective in vitro binder against mycotoxins (probably the best) since the first research on mycotoxins binders was done in the1980's.

AC also has been used in vivo showing positive adsorption results but one of the limitations of AC when used on a CONTINIOUS basis are the side effects. One of them would be the same as the use of AC at home as a water filter, the removal (absorption) of many things from water including minerals such as calcium, phosphorus etc. that would be similar outcome as using it on a continuous basis in feed.

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