Deoxynivalenol, a Risk Mycotoxin for Children. Analytical Methods. Deoxynivalenol Levels in Wheat-Based Food Products

Published on: 02/11/2005

Author/s : Alberto Gimeno
Technical Consultant of SPECIAL NUTRIENTS, INC, 1394 Coral Way, Miami, Florida, 33145 USA.

Description and chemistry of deoxynivalenol 4-Deoxynivalenol (DON), also known as vomitoxin belongs to trichothecenes chemical family: tetracyclic sesquiterpenes with 12,13-epoxy group, therefore the deoxynivalenol is a 12,13-epoxy-3,4,15-trihydroxytrichotec-9-en-8-one. It is produced by several Fusarium genus, especially Fusarium culmorum and Fusarium graminearum (Gibberella zea...

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Tim Calvert

February 11, 2005

I suggest a more comprehensive survey of trichothecene contamination. The lasted SCOOP task force highlighted the need for EU countries to supply more precise and frequent occurecence data in foodstuffs. The need for more viable ways of detoxification should also be highlighted. Research from this lab and our recent pulibcation (mycopathogia) suggests that TDI may have to be revised due to the cytotoxic effect of DON and T-2 at <= to 100ng/ml over 2 day incubation on human monolayers (HEp-2 HeLa and CaCo-2). Also better analytical and more importantly a STANDARD technique should be investigated to retrieve more significant and more sensitive results.....

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