Deoxynivalenol, a Risk Mycotoxin for Children. Analytical Methods. Deoxynivalenol Levels in Wheat-Based Food Products
Published: October 3, 2004
Summary
Description and chemistry of deoxynivalenol 4-Deoxynivalenol (DON), also known as vomitoxin belongs to trichothecenes chemical family: tetracyclic sesquiterpenes with 12,13-epoxy group, therefore the deoxynivalenol is a 12,13-epoxy-3,4,15-trihydroxytrichotec-9-en-8-one. It is produced by several Fusarium genus, especially Fusarium culmorum and Fusarium graminear...
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Authors:
Alberto Gimeno
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11 de febrero de 2005
I suggest a more comprehensive survey of trichothecene contamination. The lasted SCOOP task force highlighted the need for EU countries to supply more precise and frequent occurecence data in foodstuffs. The need for more viable ways of detoxification should also be highlighted. Research from this lab and our recent pulibcation (mycopathogia) suggests that TDI may have to be revised due to the cytotoxic effect of DON and T-2 at <= to 100ng/ml over 2 day incubation on human monolayers (HEp-2 HeLa and CaCo-2). Also better analytical and more importantly a STANDARD technique should be investigated to retrieve more significant and more sensitive results.....
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