Eduardo Frandi Butolo

Pirzado M Zakria thanks for your question. Most exogenous proteases in the market at endo-acting alkaline peptidases i.e. they do not generate free amino acids like an exo-acting protease and they more closely resemble trypsin and chymotrypsin than alternative endogenous proteases like pepsin. They work by improving the solubility of dietary protein which would otherwise escape digestion e.g. pr ...

Leon Broom thanks for your question and nice to hear from you again. Hope all is well with you also. Most of the microbiome-associated research has been done in the carbohydrase space and similar work for phytase and protease is limited. In our work we do see changes in the microbiome function (functional meta-genomics) associated with protease. This is related to changing nitrogen flow dynamics t ...

Totally agree with you, Aaron. Pepsin is an endoprotease at hydrophobic amino acid centers, Chymotrypsin is very complementary by acting at the amino the end of resulting chains where the hydrophobes are accentuated. Typically, the hydrophobes are also in the greatest proportion of most proteins while resulting changes act to improve overall compatibility with water to enable all other enzymes to ...

Ghorbanali Sadeghi, if you reflect on the carbohydrase market, there is a great diversity of enzymes available that have been developed specifically to address the heterogeneity in the substrate landscape - from xylanase, glucanases, pectinases, galactosidases, mannanases, etc. We understand that dietary carbohydrate is not a homogenous substrate pool. With protein we still have some work to do he ...

Energy is not matter but is contained in matter. Metabolism of amino acids, fatty acids, and glucose provides energy in animals in a cell- and tissue-specific manner. So, we need to understand adequately animal biochemistry, particularly the efficiency of metabolic transformations of energy in poultry and livestock species. Please read my recent interview with Engormix on this topic.