Antimicrobial peptides as an alternative to relieve antimicrobial growth promoters in poultry

Published on: 11/18/2021
Author/s : N. Nazeer 1; S. Uribe-Diaz 1,2; J. C. Rodriguez-Lecompte 2 and M. Ahmed 1 / 1 Department of Chemistry, University of Prince Edward Island, Charlottetown, Canada; 2 Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada.

IntroductionPoultry producers attempt to control infectious diseases through a variety of means, including appropriate farm management practices and breeding genetically resistant lines (Sartika et al. 2011; Scott et al. 2018). Unfortunately, existing farming conditions favour increased chicken densities in poultry houses, increasing the risk of spreading entero-pathogens such as Salmonella and Cl...

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Sumit Sipany Sumit Sipany
Product Executive - Marketing
ABTL Advanced Bio-Agro Tech Ltd ABTL Advanced Bio-Agro Tech Ltd
Pune, Maharastra, India
November 18, 2021

BPPS Forte product from ABTL is the best bioavailable protein peptide system.

A. BPPS Forte is a poly-nutritional feed supplement produced by hydrolysis of proteins (soybean meal) at specific locations with the help of microbial enzymes into bioactive peptide fragments which can be effectively utilized.

B. BPPS Forte possesses higher bioavailability leading to rapid absorption in the bird's digestive system thereby bringing wide range of physiological functions & elicit performance significantly.

C Bioactive peptides shown antioxidant and anti- Effect of BPPS Forte supplementation in broiler feed Inflammatory effect by inhibiting nuclear factors –kappa B and blocking the secretion of pro-inflammatory cytokines in an oxidative-stress.

D. In summer feed formulators are reducing crude protein % in poultry diet with extra supplementation of amino acids to minimize negative impact of heat stress due to high heat increment effect of protein. To overcome productive losses easily digestible hydrolyzed proteins can be added in poultry diet.


Conclusions:

A. Supplementation of BPPS Forte in broiler diet improved the growth performance i.e. body weight gain and FCR.

B. BPPS Forte supplementation in layer diet improved body weight gain in pullet birds and reduced total number of pullet eggs and thus helped in improving egg production
parameters.

C. Supplementation of BPPS Forte in broiler and layer diets helped to increase profitability by improving production performance.

Reply
November 18, 2021

Dear Sumit Sipany,

Reading your note, I would like to ask you the favor to elaborate/explain more the concept: "Bioactive peptides shown antioxidant and anti- Effect of BPPS Forte supplementation in broiler feed Inflammatory effect by inhibiting nuclear factors –kappa B and blocking the secretion of pro-inflammatory cytokines in an oxidative-stress". In my opinion, is clear that the inhibition of NF-kB signalling may cause severe side effects in humans. Therefore, a much better understanding of the mechanism of your product underlying the pathological activation of NF-kB in individual diseases is crucial; the solution to a natural/homeostatic mechanism (pro-inflammation) cannot be worse than the solution inhibiting it.
Could you explain what are the more important or determinants feed inflammatory effects?

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