The Russian authorities plan to begin slaughtering poultry on Tuesday in 18 Siberian villages where bird flu has been detected.
The strain found in the Novosibirsk region has been identified as H5N1 - the type that has killed at least 57 people in South-East Asia since 2003.
An outbreak of bird flu has also been reported in neighbouring Kazakhstan.
Russian doctors suspect that migratory birds brought the virus to Siberia, where poultry is now in quarantine.
No human cases of the disease have been reported so far in Siberia. The affected villages are in the Dovolensky, Kupinsky, Zdvinsky and Chistoozyorny districts.
There are fears of a global pandemic stemming from the H5N1 type, if it mutates into a form which could spread easily from human to human.
Most of those who have died in Asia are believed to have contracted the virus directly from birds.
A man who worked on a chicken farm in Kazakhstan is seriously ill in hospital and local health officials fear he might have contracted bird flu, the Russian website Newsru.com reports.
He came from Golubovka village in the Pavlodar region, where 600 geese have died of bird flu, officials say.
