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The pathogenesis of porcine circovirus type 2 (PCV2) infections in pigs is still not completely understood. PCV2 has a tropism for lymphoid tissues where it is associated with depletion of follicles and histiocytic infiltration thereby accumulating in large numbers mainly in the cytoplasm of macrophages (1).PCV2 belongs to the Circoviridae family and is one of the smallest known single-stranded DNA viruses (2). Since the virus lacks its own enzymes,...
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Veterinarians and pork producers can now help prevent Porcine Circovirus Type 2 (PCV2) viremia with the convenience of a single dose. New Fostera TM PCV from Pfizer Animal Health is the result of the company's commitment to best practices and continuous quality improvements.
"Nearly all pigs are exposed to PCV2 during their lifetime, so the goal is to create an environment with the least amount of virus present,"...
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Introduction Through the late 1990's and on into the present century the global swine industry experienced very profound changes. The price crash in 1997/98 was especially traumatic and the outbreaks of CSF and FMD were also particularly damaging. A new emerging disease that became known as Post-weaning Multi-systemic Wasting Syndrome (PMWS) and its related Post-weaning Dermatitis Nephropathy Syndrome (PDNS) then appeared all over...
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The porcine Circovirus type 2 (PCV2) is considered an important emerging pathogen in swine production. It has been associated to different syndromes and porcine diseases like the Porcine Dermatitis and Nephropathy Syndrome (PDNS) and the Post weaning Multisystemic Wasting Syndrome (PMWS). There have been found other infectious agents associated to PCV2, like the Aujeszky's disease Virus (ADV), Porcine Parvovirus (PPV), Porcine Reproductive Respiratory Syndrome Virus...
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Porcine circovirus type 2 (PCV2) is a small, circular, single-stranded DNA virus that affects pigs worldwide and is economically important to the swine industry. Within the past 3 years, North America has seen a marked increase and wide dissemination of PCV2-associated disease (PCVAD) that has resulted in devastating production losses. The rapid spread of PCVAD raised important questions about transmission of PCV2 amongst swine populations and regions. To date, transmission of PCV2 is not well...
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Several trials in Kansas have demonstrated that circovirus vaccination improves the performance of growing pigs even on high health farms. On a 300 sow, PRRS negative farm with a history of PCVAD, 235 animals were vaccinated with a porcine circovirus type 2 (PCV2) vaccine at three and six weeks of age. They were housed in the same pens as 250 control (non-vaccinated) animals. Mortality rate and growth rate were significantly better in vaccinated pigs. In the wean to finish stage, the...
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A pig virus that exists worldwide has become more dangerous as the virus has mutated and then combined with other pathogens, according to Purdue University researchers. It's not known why a virus that has been known to infect swine for almost 40 years in North America suddenly started causing disease in young pigs in 1991 and then began mutating into more deadly forms. Evidence from research being conducted at the Indiana Animal Disease Diagnostic Laboratory on the Purdue campus has...
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Intervet Inc. announced yesterday the full U.S. Department of Agriculture license for Circumvent PCV (Porcine Circovirus Vaccine, Type 2, Killed Baculovirus Vector), which provides a superior solution for the control and management of Porcine Circovirus Associated Disease (PCVAD). The vaccine is labeled as "For use in healthy swine, 3 weeks of age or older, as an aid in the prevention of viremia and as an aid in the prevention of virus shedding caused by Porcine Circovirus." ...
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Within a few years, post-weaning multi-systemic wasting syndrome (PMWS) has become a worldwide animal health concern to the pig industry and a real challenge to the veterinary science community. A small single-stranded DNA virus, Porcine Circovirus type 2 (PCV2), was rapidly found in the damaged tissues of affected pigs. However as soon as the laboratory tools adequately tailored to PCV2 detection on a large scale were available, it became evident that the virus was widespread and...
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Yesterday, Boehringer Ingelheim Animal Health announced the launch of the European PCV-2 Award, which recognizes excellent research proposals in the area of applied immunological PCV-2 research. In total, the winners will be awarded with 75,000 Euro, three prizes of 25,000 € each will be granted to those European researchers that suggest innovative approaches in the field of swine immunology to explore Porcine Circovirus Diseases (PCVD) or PCV–2 associated diseases. With the...
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Help is on the way for pork producers battling porcine circovirus associated disease (PCVAD).
A joint study with Iowa State University and Boehringer Ingelheim Vetmedica Inc. in St. Joseph, Mo., has indicated other swine diseases play a key role in PCVAD occurrence and severity. The announcement was made during the World Pork Expo on June 8.
In addition to porcine circovirus type 2 (PCV2), other diseases such as porcine reproductive and respiratory syndrome (PRRS), salmonella and...
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Porcine circovirus is 'everywhere,' one expert says, leading three animal health companies to increase production of the treatment. A hard-to-kill virus sweeping through hog herds worldwide is meeting its match: a vaccine that is very effective, but short in supply. The virus, known as porcine circovirus, is "everywhere," said Dr. R.B. "Butch" Baker, senior clinician at Iowa State University's food supply veterinary service. "This thing...
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Boehringer Ingelheim Vetmedica, Inc. (BIVI) announced this week that it has received approval from the U.S. Animal and Plant Health Inspection Service for a new vaccine called Ingelvac CircoFLEX to protect swine against diseases caused by porcine circovirus type-2 (PCV2).
According to Klaas Okkinga, BIVI marketing manager, Ingelvac CircoFLEX is a single-dose vaccine that provides efficacy and safety to pigs.
"It's effective in immunizing pigs as young as three weeks of age prior to...
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The introduction of two new vaccines appears to have turned the tide in the battle to contain a potentially deadly condition that has taken a dramatic toll on swine herds around the world. Porcine Circo Virus Associated Disease (PCVAD), previously called Post-weaning Multisystemic Wasting Syndrome (PMWS), is a viral disease which typically affects young pigs, weanlings, from eight to 16 weeks of age. However symptoms tend to manifest themselves in the grower phase and the disease is...
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A preconference workshop focused on Postweaning Multisystemic Wasting Syndrome (PMWS) was held at the American Association of Swine Veterinarians’ annual meeting in Kansas City, Mo.
The presentations included in the workshop supported the following points:
• PMWS is not a food safety or public health issue.
• PMWS associated with Porcine Circovirus-2 (PCV-2) has been present in the U.S. since the 1990s.
• A more severe form of the disease has recently been reported in eastern Canada...
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Boehringer Ingelheim Vetmedica, Inc. announces the launch of a new research program targeted at porcine circovirus associated diseases (PCVAD), a disease complex that presents a growing threat to the health of swine in the United States and other countries.
As part of the research initiative, called the PCVAD Research Award Program, Boehringer Ingelheim is committing $75,000 annually to fund three selected research programs. The program is open to all swine researchers, veterinarians,...
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A newly activated virus sweeping through hog country is the wild card for continued pork profits, according to a veteran hog industry analyst.
U.S. pork exports and domestic demand also will play a role in determining if more than two years of hog profits will continue.
Glenn Grimes, an agricultural economist who is a professor emeritus at the University of Missouri and a consultant for the pork industry, said the impact of the virus, known as Porcine Circovirus Type 2, could throw a...
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The Canadian introduction of the first of a number of new vaccines designed to protect against PMWS is offering hope to those farms facing a heightened risk of infection.
Post-weaning Multisystemic Wasting Syndrome, a relatively new condition which was first characterized in Western Canada just over a decade ago and which is now present worldwide, only affects pigs.
Symptoms typically occur between about six and 15 weeks of age, when the pig enters the nursery or early grower phase and...
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A quick email survey of pig vet specialists suggests that finisher mortality rates have increased this winter and in particular the number of sudden deaths in otherwise “good” pigs.
Cases investigated seem to have been of acute respiratory disease (Pasteurella, Strep suis Haemophilis parasuis and APP have been isolated), PDNS and bloody gut (the increased amount of wheat or the new strains fed possibly involved?). In Scotland there have been a few herds with increases in PDNS and late PMWS...
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