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Gut integrity, intestinal microbiota and intestinal barrier or the strategy for enhanced performance and reduced medication and ZnO

Published on: 09/09/2018
Author/s : Dr. Milena Sevastiyanova

Abstract The gut carries an important responsibility in selecting what can be absorbed and what should remain outside the body. To put this in the right perspective, it is important to note that the surface of the intestinal tract is 300 times the size of the surface of the skin. Post-weaning diarrhoea (PWD) causes mortality and morbidity in pig production and is a reason for regular antibioti...

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September 12, 2018

Good story, with consistent fundamentals. However, I have some doubts about what I would like to clarify. - There is no doubt about the bactericidal action of short chain (acc) and medium chain (acm) acros. My question as a researcher is that normally the immune challenge of the animals in the experiment is appreciably less than the field level, in which case the acc and acm may prove as efficient as the antibiotic. Furthermore, in the farm, besides the possible difference in the immune challenge, other factors such as density of animals in the nursery cage, the availability of feeder and the mixture of animals from different litters, among other factors, may contribute to compromise the efficacy of the acrylics in replace the antibiotic or Zno.
I understand that antibiotic dysbiosis is a potential risk for piglets, considering that healthy microbiota is essential to ensure a good performance of the animals, which can be obtained using the acc and acm, the doubt, if I I did understand, is that in the case of replacing the antíbiotico by acc and acm, other details of management should be observed in order to reduce the stress level of the animals.

December 6, 2019
Dear Dr. Milena Sevastiyanova,

Thank you for the article. I feel that the conclusion that the product Luminance can replace Colistin has not been shown effectively in this trial. As the PWD symptoms were not seen the use of colistin was unnecessary and so it cannot be concluded that the product provided an effective replacement. Also there are no stats or negative control in this study so it is hard to know if a treatment with neither product would perform equally well.
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Jon Bergstrom
Jon Bergstrom
Swine Nutrition & Production, Ph.D.
  Plano, Texas, United States
Gut Health Intestinal health is the most determining factor for anima...