Gut Health and the Post-Weaning Transition in Piglets

Published on: 08/09/2021
Author/s : John R. Pluske / College of Science, Health, Engineering and Education, Murdoch University, Murdoch WA 6150, Australia.

Introduction A gastrointestinal tract (GIT) that functions in an optimum way clearly is of importance to the overall metabolism, physiology, disease status and performance of pigs of all stages of growth and development, and especially in the sensitive post-weaning production period. Disruptions (dysbiosis) in the GIT after weaning caused by internal and external influences can cau...

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August 9, 2021
The beginning of the piglet intestine inflammatory process begins with the production of phospholipase 2A (PLA2).
Following activation dentritche cells and macrophages IL 2 and granulocyte netrofili arrival in the basal lamina with release of ROS.
Simultaneously, the dysbiosis following the food change involves a dell'immunotolleranza stopping and thus also provides you with an inflammatory process.
In severe cases the presence of ROS leads to a mutation of the bacteria as E. coli which through the lambda phage becomes enterotoxigenic.
Lock upstream the production of PLA2 allows to wean piglets without addition of antimicrobials.
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Casey Bradley
Casey Bradley
Doctorate - Animal Science - Monogastric Nutrit...
  Springdale, Arkansas, United States
 
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