Evolution of Pathogenicity of Avian Influenza Virus and Control
Thierry van den Berg /
Veterinary & Agrochemical Research centre
Groeselenberg 99, 1180 Uccle, Belgium
The genus influenza belongs to the Orthomyxoviridae family, representing viruses that have a single-strand, negative sense, and segmented RNA genome. RNA virus replication is characterized by high mutation rates, short generation time, and high progeny yields. In addition to mutations introduced by their errorprone polymerases without proofreading capacity, ...