Organic acid (OA) are generally consider as a safe alternative to antibiotic and therefore, most member state of European Union (EU) have approved their use. Present study investigated the outcome of OA blend on modulating liver, renal physiology and the intestinal integrity of Japanese quail (Coturnix coturnix japonica). Results of the present study reveal that serum Alanine aminotransaminase (ALT), Aspartate aminotransaminase (AST) showed a significantly lower value in quail supplemented OA-1, OA-2 and OA-3 as compare to the values noted in OA-0 group. Similarly, serum urea and creatinine values were significantly lower in the treated groups as compare to the untreated quails. OA supplementation in the drinking water of quail significantly improved the histo-morphology of liver and gut. The height of villi was higher in the groups given organic acid in the drinking water as compared to the quails given plain drinking water. The quails given plain drinking water showed vaculation in the hepatocytes while this change was lower in the birds given organic acid mixed water. Hepatocytes showed foamy appearance of cytoplasm with normal sinusoidal spaces. The findings of the present study suggested that addition of organic acids in the drinking water improve overall health and performance of the quails in all doses.
Keywords: Organic acid; ALT; AST; Urea; Critinine; Quail