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Isoleucine Plays a Critical Role in Low-Protein Diets

Published: June 27, 2025
By: Ronnick Fong, HANGZHOU DE MARK INDUSTRIAL CO LTD.
Isoleucine Plays a Critical Role in Low-Protein Diets. - Image 1
In low-protein diets, isoleucine often becomes a limiting amino acid due to excessive leucine or free valine. Appropriate isoleucine supplementation promotes protein synthesis, improves feed conversion efficiency, and enhances animal growth performance.
Research demonstrates that 28-day-old weaned piglets fed diets with a 55% SID(Standardized Ileal Digestibility) isoleucine/lysine ratio show superior growth performance compared to those fed 51% ratio diets. Even under low-protein conditions, isoleucine supplementation maintains or even improves weight gain. (Yang Jing, Xie Gaomiao, Li Jie, et al. Evaluation of Isoleucine Requirement in Pigs under Different Low-Protein Levels [J]. Guangdong Feed, 2022, 31(12): 31-34.)
Studies from Wageningen University indicate that with adequate isoleucine, dietary protein levels for nursery pigs can be reduced to 15%, with the optimal isoleucine requirement for piglets being 6.18 g/kg (below NRC recommendations). However, excessive leucine competes for metabolic enzymes, reducing isoleucine utilization, necessitating balanced ratios among these three amino acids.(Isoleucine: A missing link in the pivotal role of amino acids in safe weaning. Trigga.[2022-06-30])
Precise isoleucine supplementation optimizes amino acid balance in low-protein diets, reduces protein waste, and ensures optimal animal growth.
We specialize in supplying a range of feed-grade Amino Acids, including L-Lysine, L-Threonine, DL-Methionine, Arginine, Tryptophan, Valine, and Isoleucine.
For your convenience, we accept full-container-load (FCL) orders for individual products, as well as offer support for combined container shipments containing a mix of various amino acids. This flexibility ensures that you can efficiently meet your specific needs.
All these products adhere to China national quality standards (GB), guaranteeing top-notch quality. Our commitment to punctual delivery ensures that we meet and exceed the customers' diverse requirements seamlessly.
We take pride in addressing both your cost and quality concerns.
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Authors:
Ronnick FONG
Hangzhou DE Mark Industrial Co Ltd
Hangzhou DE Mark Industrial Co Ltd
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