David Bean

INTRODUCTIONPolymyxin B and E (colistin) are cationic antimicrobial peptides currently reserved as a last resort treatment for serious infections caused by multi-drug resistant Gram-negative bacteria (Poirel et al., 2017). Although colistin has been used in human and veterinary medicine for over 50 years, it has recently become increasingly important in the treatment of infections with carbapenem- ...