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INTRODUCTION Porcine epidemic diarrhea virus (PEDV) causes an acute and highly contagious enteric disease, which is characterized by severe enteritis, vomiting, watery diarrhea and a high mortality rate in neonatal piglets. Belonging to the family Coronaviridae, genus Alphacoronavirus, PEDV has a single-stranded, positive-sense RNA genome of ∼28 kb that encodes four structural proteins, s ...
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