Vaccines for different Salmonella serotypes

Name: Vaccines for different Salmonella serotypes
Uploaded: 3/5/2020
Description: Manuel Da Costa (Zoetis) commented on trials done with five serotypes to improve poultry protection, during IPPE 2020 in Atlanta, USA.

Topic: Salmonella in Poultry

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Manuel Costa

University of Georgia

At: IPPE - International Production & Processing Expo 2020

Graichi Chabane

June 22, 2020

Yes, of course.

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Mohammed alhajj
PhD

June 22, 2020

Is there a suggested vaccination programme for broiler chickens?

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Yusuf Ibrahim

June 23, 2020

How readily available is the vaccine going to be, especially in Africa?

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Muhammad Hassan

June 27, 2020

Dear sir

Please share how much serotypes of salmonella that vaccine control and please also share it's MOA and contra indications
Regards
Hassan

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Dr.ir.J.R. van Herwijnen

June 27, 2020

We already tested many multivalant serotype vaccines in broilers and pigeons, best challange protection is obtained by oral vaccines using potent adjuvants based on ISCOM technology
These vaccines induce protective IgA and GALT and MALT response and protect 12-16 month depending on salmonella pressure.
If this is used together just before immune gap with probiotics 7-8 strains specially isolated from birds, all strains have different antibiotic resistance so these will stabilize the intestinal flora and make intestinal flora little acidic in many case bacterial problems are solved
For evaluation we have two products available one for reducing heamolitic coli and one for Salmonella
If you like to receive more information about these studies or products or if you want to work together let me know.

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Muhammad Hassan

June 27, 2020

Dear Dr van

Thanks for sharing and needs more inputs regarding that vaccine like its incubation time and you also discussed on microflora means that is additional cost with vaccine. And my openion is if bird microfloras are higher side than through good management we can protect the bird form salmonella. Hope so you have much experience please share in further details
Regards
Hassan

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Dr.ir.J.R. van Herwijnen

June 27, 2020

Dear Muhammad Hassan,
You are right depending on the situation and feed used just vaccination is not enough to keep out bacterial diseases. Oral vaccine is depending on aim, broilers or layers given twice or three times, usually just a single time isn't enough for layers . In broilers sometimes it is, however it's improvement is increased if you use during a small time frame probiotics to improve intestinal stability and increase feed conversion
During several experiments we have shown that if 76% of the birds is immune, it is enough to protect the rest of the animals. Although we prefer to have an immune protection of close to 100%
It has been shown that if the microflora of the birds is optimized the birds are less vulnerable for salmonella campylobacter and coccidiosis

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