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Genomic characterization and molecular epidemiology of Gumboro’s disease

Published: September 12, 2016
Source : www.irta.cat
A doctoral thesis, directed in IRTA-CReSA, proves that highly virulent IBDV comes from Asia. The doctoral thesis dissertation of Jennifer S. Toskano Hurtado explained this investigation. The thesis was entitled “Caracterización genómica y epidemiología molecular del virus de la Bursitis infecciosa en España” (Genomic characterization and molecular epidemiology of infectious bursal disease virus in Spain) and was directed by Natalia Majó and Jose Ignacio Núñez, researchers from IRTA-CReSA.
The thesis provides important contributions to the understanding of the epidemiology of avian infectious bursal disease (IBDV), also known as Gumboro’s disease, which causes a disease of great importance in poultry production. An important contribution of this thesis is the sequencing and analysis of over 950 strains of IBDV, allowing a thorough overview of the circulation of these viruses in the field. On the other hand, phylogeography studies have been able to prove the origin of the highly virulent IBDV, opposite to what was assumed; these viruses come directly from Asia and not from northwestern Europe, thus demonstrating the utility of these techniques in virus knowledge and disease control.
This thesis has also contributed to the increase of complete genomes available for this virus. Among the results obtained, one must highlight the first description of the phenomenon of virus recombination isolated in Spain, a phenomenon not described so far. All this information is very important for future research on the knowledge of different aspects related to the control of the virus, from its pathogenesis to its virulence and vaccine design, among others.
Source
www.irta.cat
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Ismet Mamode
Food & Allied Group of Companies
16 de septiembre de 2016
IBD vaccination BROILERS DAY 12 - IBDL - from CEVA - Drinking water DAY 16 - IBDL - from CEVA - Drinking water OR DAY OLD - HATCHERY - TRANSMUNE DAY 24 - IBDL - from CEVA - Drinking water LAYERS DAY OLD - VAXXITEK - HATCHERY DAY 24 - IBDL - from CEVA - Drinking water
Dr. Jignesh Barot
15 de septiembre de 2016
Informative. Thanks. Kindly explain how to design IBD vaccination schedule for Commercial broiler as well as commercial layer.
Ismet Mamode
Food & Allied Group of Companies
15 de septiembre de 2016
This study has proved that the vvIBD virus had originated from Asia. But is it possible to define the Asian countries from which these pathogens had occurred? Thanks to the efficient measures taken by the industry and by all those concerned, this disease is now under control in many countries in the world. There is no alert from the OIE. Let us hope that our poultry will be safe from that disease. Biosecurity is necessary.
Boudaoud
14 de septiembre de 2016
As well as the phenomenon of reassortment, I think that virus recombination concerning IBDVs, was already described. as an exemple, Some strains isolated in Latin America between 2001 and 2011 exhibited, within the hypervariable region of VP2, a combination of amino acids borrowed from classic and variant viruses
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