Klaudia Chrzastek

Avian influenza virus (AIV) belongs to Orthomyxoviridae family and is characterised by containing negative-sense, single-stranded RNA genome of 8 segments that encode for 10 structural and at least 9 nonstructural/regulatory proteins. Hemagglutinin (HA) and neuraminidase (NA) that are the most abundant and immunogenic surface protein, and are involved in virus entry and exit from the cell. There a ...

Avian influenza viruses (AIVs) are classified as either low-pathogenicity (LP) or high-pathogenicity (HP). LPAIVs generally cause mild infections, whilst HPAIVs can cause high mortality in a wide range of avian species. AIV subtypes are defined based on their surface glycoproteins, haemagglutinin (HA; H1-H16) and neuraminidase (NA; N1-N9), and HPAIVs appear restricted to the H5 and H7 subtypes. HP ...