Sukumar Karanth

Natural killer (NK) cells, an important component of innate immunity, are a distinct lineage of lymphocytes defined by the expression of CD56 and NKp46 and by the absence of CD3, providing a first line of defense against pathogens and cancer in a non-major-histocompatibility-complex- (MHC-) restricted fashion without the need of prior sensitization. Derived from the bone marrow, NK cells have wide ...