Jose Eduardo Butolo

HypothesisGuanidinoacetic acid (GAA) is synthesized in the liver and kidneys from arginine (Arg) and glycine (Gly) and subsequently methylated by S-adenosylmethione to creatine (2). Heat-stressed birds respond to the presence of higher uric acid concentration and changes in electrolyte balance by increasing the usage of osmoprotectants.These osmolytes are viable endogenous precursors for Gly (3). ...