Article published the March 28, 2025
Introduction: Chemosensing in the gut involves G protein-coupled receptors and their associated G proteins, including taste 1 receptors (T1Rs) and taste 2 receptors (T2Rs). Sweet taste is recognized by T1R2+T1R3 heterodimers and umami flavors by T1R1+T1R3 heterodimers; however, bitter perception is detected by an array of T2Rs. Advances in gastrointestinal chemosensing have uncovered mechanisms by ...
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