Maternal Antibody Interference in Newcastle Disease Vaccination

Published on: 08/14/2019
Author/s : Pranjal Pranbindu Kalita 1, Biswajit Barkataky 2. / 1 In charge, Labnetic Lab. Raipurani Road, Barwala, Panchkula. Haryana, Pin: 134118; 2 Idexx Laboratories Inc.

Introduction Maternal immunity for Newcastle Disease (ND) can be quantified with Haemagglutination Inhibition(HI) test. Titres are expressed as log 2 values. Titres in a group are analysed statistically and mean titre in a group depicts status of flock immunity. Quantification of HI titre at day old age and subsequent quantification at weekly interval can determine the maternal antibody interfere...

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August 14, 2019
l think it was better to collect blood samples at 1st , 10th , 15th & 20th days..l suggest to include ELISA Test at same time on the same samples to compare the results..l think the results will be much clear & nearly accurate.
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August 14, 2019

Did you check whether this affects the sub conjunctival or intra ocular means of vaccination with B1 hitchner or B1 lasota? I guess strongly that subconjuctival immune glands called haderian gland will prevent the antigen to get to the bloodstream for antisera attack. Could you please discuss this?

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August 15, 2019

Good work. day old live vaccine can be a reason for the failure of vaccine as it is neutralized by mab.
Many people are now a days attributing the failure to emergence of new strains of nd which may require revision in the thinking. n.d is known to be a single strain for a long time.

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Juvy Lago Juvy Lago
Doctor of Veterinary Medicine
August 18, 2019
i think the brand of vaccine used in this trial also matters.
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August 18, 2019
The vaccintaion method at DO (group A) and at 7 days (group B) wasn't mentioned in the Materials and Method - by eye drop? or spray?. if it spray - same droplet size at DO and 7 days?
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