Discussion created on 03/24/2018

LPAI

How control and treated LPAI outbreak of breeder ?

Anonymous query
Bangladesh
Specialist in Animal Nutrition
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Brett Hopkins Brett Hopkins
Sr. Technical Services Manager for Project Horizon in North America
Novus International Novus International
Missouri, United States
March 24, 2018
If you would like to discuss details you can email me at Brett.Hopkins@novusint.com
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Santiago Sievert Garcia Santiago Sievert Garcia
Bachelor of Science in Animal Husbandry
March 24, 2018
Could you please provide some more details as: What type of flock system (closed tunnel ventilated houses; open sidewall housing; free-ranged system); single age or multi-age farm; age of the birds and replacement program; Feeding and watering systems; vaccination programs; vaccine regulations ( whether AI vaccines are legal or not); Distances between houses and if multi age systems whether replacement flocks are brooded and grown separately in another farm ( distance of rearing farm); current state or condition % of flocks/birds affected; Whether Broiler breeders or Layer Breeders;etc.
With these details, we would be able to have a clearer picture of the problem and will be able to give you a more appropriate answer.
Or you can send me an email at sansigar@yahoo.com to protect your confidentiality!
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Athangudi Venugopalan Athangudi Venugopalan
Animal Health Technologist
March 24, 2018

LPAI IS LOW PATHOGENIC ONLY IN SPF AND NOT IN COMMERCIAL.DUE TO CO INFECTION WITH BACTERIAL OR VIRAL AGENTS BY EXACERBATION THE MORTALITY MAY REACH >80% BY EXACERBATION.UNDER FIELD CONDITIONS CONTROL IS ELEVATED LEVEL OF BIO SECURITY COVERING FEED/WATER AND ENVIORNMENT
CHOICE OF DISINFECTING AGENTS -CHLORINE DIOXIDE OR ITS SISTER PRODUCT ACIDIFIED SODIUM CHLORITE AND MMS. THERE ARE ONLY 6 CHEMO STERILANTS- ETHYLENE OXIDE/CHLORINE DI OXIDE/PER ACETIC ACID/HYDROGEN PEROXIDE/GLUTERALDEHYDE AND FORMALDEHYDE. OUT OF 6 ONLY 2 ARE FOOD GRADE -CHLORNE DIOXDE AND PER ACETIC ACID. AS ON DATE MOST POWER FULL GERMICIDE EVOLVED BY MAN IS CHLORINE DIOXIDE.NO ESIDUE/NO RESISTANCE/ACTIVE IN PH RANGE 4 TO 10//ACT EVEN IN PRESENCE OF BIO FILM AND ORGANIC MATTER/ NO FORMATION OF CARCINOGENS [TRI HALOMETHANE AS IN THE CAS OF CHLORINE./CS EFFECTIVE AND APPROVED BY NATIONAL AND INTERNATIONAL AGENCIES.FEED SANITATION WITH FORMALIN OR CHLORINE DI OXIDE OR THREE IN ONE IS ESSENTIAL. AS AND WHEN WEEKLY MORALITY GOES ABOVE 0.1% INITIATE CONTROL MEASURES BY CHLORINE DI OXIDE SPRAY OF LITTER/ AERIAL SPRAY OF ACIDIFIED SODIUM CHLORITE AND WATER SANITATION BY MMS AND FEED SANITATION BY FORMALIN. WITH IN 4 DAYS THE MORTALITY WILL COME DOWN. CHLORINE DI OXIDE/ ACIDIFIED SODIUM CHLORITE AND MMS CAN BE GENERATED FROM SODIUM CHLORITE AND ACDS SUCH AS CITRIC ACID OR HYDRO CHLORIC ACID. 
A.T. VENUGOPALAN

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adriaan olivier adriaan olivier
Veterinary Doctor
March 26, 2018
good morning, Yes much more info is need as state above.
some principals
bio-containment is important to prevent spread to other birds.
Maintain/ increase immunity - i.e. feed, supplements, environmental control
Stimulate immunity - vaccinate
decrease risk/ exposure - eliminate viral load in the environment
risk assessment to determine the value and impact of your decision maybe best to slaughter if riks is to high for surrounding flocks.
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Athangudi Venugopalan Athangudi Venugopalan
Animal Health Technologist
March 26, 2018
PROPHYLACTIC VACCINATION AGAINST DOES NOT CAUSES STERILIZING IMMUNITY. STERILIZING IMMUNITY MEANS AFTER VACCINATION IF VACCINATED BIRDS ARE EXPOSED TO INFECTION THERE SHOULD NOT BE DEVELOPEMENT OF VIRULENT VIRUS IN VACCINATED BIRD. BUT IN CASE OF POULTRY THERE WILLBE DEVELPEMENT OF VIRULANT AI VIRUS IN VACCINATED BIRDS EXPOSED TO INFECTION AND SUCH INECTED POULTRY ARE SOURCE OF INFECTION TO OTHER AGE GROUPS IN THE SAME FARM AS WELL AS NEIGHBOURING FARMS AS PER EU REGULATIONS POTENT AI VIRUS OF POULTRY ARE H5N1/H7N1/H5N8/H3N2 OTHER VIRUSES ARE HIN1/H7N9. HOW TO PREDICT WHICH VIRUS IS GOING TO INFECT PARTICULAR FLOCK. NO COMBIINED VACCINE
1952 TO 2002 TOTAL GLOBAL INCIDANCE OF AI IS LESS THAN 25 OUT BREAKS
BUT IN PERIOD 2003 TO 2018 REPORTES INCIDANCE OF AI IS MORETHAN 8000 CASES
ASPER WHO REPORT INDIA IS SURUNDED BY COUNTRIES POSITIVE FOR HUMAN INFLUENZA H7N9 CHINA MALAYSIA NEPAL/SIKIM AND BANGLADESH. INDIA IS AT HIT LIST OF HUMAN INFLUENZA
PRIOR TO 2005 FREE LIVING BIRDS WERE HARBOURING AI VIRUS AS CARRIER BUT NOT
INFECTED. SINCE 2005 FREE LIVING BIRDS ARE INFECTED. DURING 1918 IN INDIA HIGHEST MORTALITY DUE TO SWINE INFLUENZA H1N1 MORE THAN 5CRORE PEOPLE OUT OF 19 CRORES SUCUMBED TO SWINE IFLUEZA. SINCE JANUARY 2018
THERE IS WIDE PEVALANCE HUMAN INFLUENZA IN USA/EU/ AUSTRALIA. AS PER GLOBAL PREDICTION A PANDEMIC OF INFLUENZA IS LIKELY TO AFFECT HUMAN
NOW LPAI IS ENDEMIC AND EXACERBATED BY BACTERIAL AND VIRAL INFECTIONS. AS FOR AS TAMIL NADU IS CONCERNED LPAI IS EXACERBATED BY VARIANT EPHRO PATHOGENIC FORM OF IB.AS PER UNIVERSITY PUBLICATIONS THERE ARE MORE THAN 12 PUBLICATIONS ON PREVALANCE OF VARIANT IB. AS PER GOVT OF INDIA REPORT TO OIE NO INCIDANCE OF IB IN INDIA OVER 15 YEARS. 1900 TO 2008 CENTRAL AND STATE ANIMAL HEALTH LAWS DOES NOT COVER POULTRY SINCE DEFINITION OF ANIMALS DOES NOT COVER. AN ACT PREVENTION AND CONTROL OF INFECTIOUS AND CONTAGIOUS DISEASES WAS ENACTED. INTHE ABOVE ACT DISEASE REPORTING IS BY FARMER/ NGO OR PANCHAYATPRESIDENT. USE OF ND VACCINE LASOTA WAS BANNED AS EARLY AS1993 IN EU AND OTHER COUNTRIES. BUT IN IDIA IT IS FREELY USED. AS PER OIE ND VIRUSIS VIRULENT IF ICPI VALUE IS ABOVE O.7. IN INDIA ND VACCINE WITH ICPI VALUE 1.4 RDVK/R2B ARE FREELY USED. SUCH ND VACCINES WILL PROMOTE LPAI. AS PER OVT OF INDIA CIRCULAR DATED 2-3-04 STATE VETERINARY COLLEGES ARE APPROVED FOR DIAGNOSIS OF AVIAN INFLUENZA. NOT IMPLEMENTED. AS PER GOVT OF INDIA CIRCULAR NO PM OF SUSPECTED CASES OF AI. 5 DEAD BIRDS TO BE SENT BY SPECIAL MESSENGER BY FLIGHT TO BHOPAL,. WHERE S IN AUSTRALIA FORMALIN FIXED IMPRESSION SMEARS OF PANCREAS CAN BE SENT AND RESULTS ARE RECEIVE IN MATTER OF DAYS.NO PROPER DIAGNOSIS/ NOSURVEILLANCE. AS PER WHO REPORT H5N1 AI VIRUS INFECTION WAS SEEN AMONG POULTRY WORKERS 41 KM FROM CHENNAI NO ACTION. AS PER PUBLICATION BROILER EXPORTRTED FROM COIMBATURE WAS PSITIVE FO AI IN MIDDLE EAST DURING 2002. AS SUCH THERE IS NEED FOR ADPTION NATIONAL OR INTERNATIONAL NORMS FOR CONTROL OF AVIAN INFLUENZA IN INDIA
A. T. VENUGOPALAN
26-3-18
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adriaan olivier adriaan olivier
Veterinary Doctor
March 27, 2018
all actions should be within the scope of disease control and management of the competent authority.
it should be flexible and accommodate the characteristics of the poultry industry and sector. we should also realize the restricted capacity within governmental institutions, e.g. staff, expertise, finances and slow response times.
LPAI will always be a challenge but we are no strangers to it.
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Fred Hoerr
Fred Hoerr
DVM, PhD, Diplomate ACVP, ACPV
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