Discussion created on 10/05/2012

Mycoplasma synoviae and Escherichia coli

Forum: Mycoplasma synoviae and Escherichia Coli infection

Danka Maslic-Strizak
Veterinary Doctor
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Danka Maslic-Strizak Danka Maslic-Strizak
Veterinary Doctor
October 5, 2012

Pictures are from a 40 weeks old parental flock. Mycoplasma synoviae and Escherichia Coli infection appeared around 37th week. Deaths are approximately 1%, and spot bleeding around rib sheaths and drumstick and breasts muscles also appeared. Egg production is not reduced yet, and the quality of eggs is still good. I am starting to think that the problem has something to do with food, but I do not know how to fix it.

If anyone has experienced a similar problem, I would be grateful if I could get some advice.

Best regards, Danka

 

View entire photo album, click here

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October 9, 2012

Hello Danka,
I´ve also seen such a problem during a technical support trip to Ukraine.
The source of this infection is a hygienic problem. This agent is mostly transmitted via aerogen routes, if somebody was in flock or has poultry at home so that mycoplasma comes into an intact flock. E. coli is always present and infections appear after Mycoplasma invasion. Normally you should treat it with wide-spread antibiotics...or kill the flock. Leave the house empty for at least 3-4 weeks and vaccinate the next flock with inactivated vaccines.

Dimitri Radko

Reply
October 9, 2012

I think that case causes by:

1-defernet of flock temperature.
2-after vaccination by live vaccine.
3-aflatoxine in food do depression of imminuo system and mycoplasma appear.
4-complication of mycoplasma =Escherichia Coli infection

- you should treat with wide-spread antibiotics
-as prevention use tylosin every 21 days' medicate with it for 3 days

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Danka Maslic-Strizak Danka Maslic-Strizak
Veterinary Doctor
October 9, 2012

Dear Dmytro,

Thank you for your comment. I am sure it is a technological lapse, as usual with these problems. This time I solved the problem with antibiotics, the following flock will surely be vaccinated and if anyone is experienced with vaccination of heavy parents against mycoplasma I would like to hear about the program that was successful.
Particular problem with this farm is the fact that it is simultaneously populated with two different age groups, so if anyone has experienced vaccination in such conditions it would be valuable for me to read.
Thank you,
Danka.

Reply
Reza Fadavi Reza Fadavi
Veterinarian
October 9, 2012

HI

I think the best way to protect the flocks from such as nasty combination is to protect the parent flocks from MS and MG infection. The best way by far is vaccination against Ms with Vaxsafe MSH and against Mg with Vaxsafe TS-11. Using these vaccines must be at as early age as possible to (after 4 weeks) to prevent reinfection of Mg / Ms negative flocks with field starins. Usually No antibiotic is needed when you vaccinate your flock with these vaccinessince the incidence of such infection almost become zero. and if colibacillosis (alone) occurs Amoxycillin would be enough or you may be able to control it by looking at your biosecurity.

Reza . F. Firooz DVM MVSc
Austral Medi Vet Pty Ltd
Australia

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Danka Maslic-Strizak Danka Maslic-Strizak
Veterinary Doctor
October 9, 2012

Thank you for the advice, Danka

Reply
October 9, 2012
German Mercado MVZ;MSc.Rancho Grande Breeder Manager.Mexico.

I agree the best way to work such a problem is to vaccinate against M.synoviae and M.gallisepticum at 4-5 wks of age,chek the chix they have to be clean from mycoplamas before vaccination and avoid the use of antibiotics against mycoplasmas..The ts11for Mg and vax safe for synoviae are vaccines that work fine.

Reply
Dr.M. Saravanan Dr.M. Saravanan
Master of Animal Biotechnology
October 10, 2012
Dear Dr Reza & Dr.German,

In using TS 11 for Mg in Multiple rearing flocks, to introduce / withdraw whether it has any negative impact on farm? that means if we have to vaccinate to all flocks on introduction of vaccine?

Thanks,

Saravanan Mohan.
Reply
Reza Fadavi Reza Fadavi
Veterinarian
October 10, 2012
Hi

No,it does not have any negative impact. It is one of the safest vaccines that I have ever worked with.
Reply
Dr.M. Saravanan Dr.M. Saravanan
Master of Animal Biotechnology
October 10, 2012
Thanks Dr.Reza! Once if we introduce TS 11, we need to continue throughout or at any point of time we can withdraw from farm schedule?

Thanks!
Reply
Ram Prasad Poudyal Ram Prasad Poudyal
Veterinary Doctor
October 10, 2012

As photograph there are two solution
1. Immediate solution : According to your law is it restricted or not In Nepal we are trying by injecting this solution
gentamicin 100 ml Amikamycin 20ml Vitamin E 12 ml Vitamin B complex 38 ml Mix it and inject 0.56ml daily for three days followed by Tylosin tartrate 100% 54gm orally for 3 days
2. Permanent solution : empty shed for 3 month regular use of water sanitizer use acidifier in feed vaccinate with E coli and mycoplasma gallisepticum and M. synovae,strict quarentine protocal should be followed
Thanks

Reply
Ali Ghafouri Ali Ghafouri
Veterinary Doctor
October 10, 2012
Hi Danka
why you say these lesions were caused by Ms and Ecoli?
which kind of test ou did?
regards
Dr Ali
Reply
October 10, 2012

Dr German Mercado.
Both vaccines are secure.I have to mention that olders flocks not vaccinated because of diferents age situation in same premise will be good to considere antibiotics against mycoplasma every 4 wks until gone in order to best control exposure. Thanks.

Reply
Tarusenga Munyanyi Tarusenga Munyanyi
Animal health technologist
October 11, 2012

Treat using antibiotics like tylosin, a combination of Tetraclyine, neomycin and chloramphenicol for 5 days. One way to control it by vaccination of bird and practices high standard of biosecurity in poultry farm . if you vaccinate and treat without observing strong boisecurity it will continue to be a problem for you

Reply
Danka Maslic-Strizak Danka Maslic-Strizak
Veterinary Doctor
October 11, 2012

Dr Ali
We worked E.coli isolation and ELISA test for Ms,
Danka

Reply
Emad Elgazzar Emad Elgazzar
MASTER and PHD degree in microbiology
October 12, 2012

Hi Dr. Danka. As you may know, the mycoplasma alone perhaps does not cause obvious problem as soon it appears but when another stress factors joins as any infection virus or bacterial the mortality begin to elevate as you mention that you isolat E.Coli,when did you vaccinate your flock ? because when we vaccinated with attenuated strain -there is some things that must be in consideration that firstly the flock must be free from M. sometimes this attenuated strain changed to variant this flurring up the problem... what about the level of biosecurity-age differences between flocks-the way of transmission of infection?

Reply
Danka Maslic-Strizak Danka Maslic-Strizak
Veterinary Doctor
October 13, 2012
Hi Emand,
here the birds are not yet vaccinated against E. coli and Mycoplasmae.
Reply
Senthilkumar Senthilkumar
Veterinary Doctor
October 15, 2012

Dear Danka,

Vaccines against mycoplasma spp. works well only where the breeder flocks are reared in all-in-all-out system. In multiage flocks on a single location it is better to follow TIAMULIN HUDROGEN FUMARATE schedule right from the first week.
Also the live vaccines should only be given to the chicks that are free from mycoplasma.

Reply
October 18, 2012
In a naive multi age rearing and nearby breeder complex what is the protocol of introducing either Mg or Ms vaccines?
Reply
Dermott Reilly Dermott Reilly
Economics & History
October 24, 2012

Interesting discussion and thanks Danka for sharing with us.
Has anyone looked into the possibility of using thin coatings on the walls and roof of poultry sheds to remove bacteria and viruses from the air? See www.ingeniatouch.com for the idea better explained (for Healthcare). I will forward a presentation from a Germany company if anyone is interested. 

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