Comments on article on Gout:-
I thank all for offering their comments on my article on Gout. I may add further as below :-
1) It is known that gout in poultry is a multifactor disease and the causes range from faulty management, feed to infection and genetic susceptibility. In this context, the PhD research work of Dr K.B.Solanki ( Retd Professor of Pathology Bombay Veterinary College, Mumbai India ) on salt toxicity, contains some relevant observations.
a) Dr Solanki tried to experimentally induce gout in commercial broiler chicks by applying separately each of the factors --- high brooding temperature ;limited drinking water supply , high protein diet ; low Vit A in feed ; high dose of Nitro furans—but none of these produced gout in chicks. This indicated that at least two or more factors operating simultaneously cause gout. Further research in this direction is needed to isolate very important and frequent combination of causes of gout .
b) In another study, Dr Solanki observed that histological structure of kidney ( number of glomerulii per unit area ) and hence renal function capacity, differs in different breeds of commercial broiler chicks. This indicates a genetic susceptibility as co-factor in gout.
2) As regards infectious cause of gout , we have been vaccinating all batches of broiler breeders with IB and IB nephro vaccines. In couple of commercial broiler batches, IB vaccine on day old has also been tried but the gout continues. Involvement of IB and other nephropathic agents—Scepticemia , IBD , Ochratoxins should be investigated in all severe outbreaks of gout.
3) Gout was not a major problem in 1980-90s as t is now. Present day broilers are genetically different, have much higher growth rate, lower FCR and lower mortality than birds of 80s and 90s. The present day feed is also higher in crude protein
( particularly Pre-starter ), and high in calories. However broiler management in India has not caught up and we still stick on to provide space of 0.5 Sqft and even less per bird in brooding stage. Whether these developments also have made the flocks more prone for gout.?
4) Variable incidence :- In same locality farms with common source of chicks and feed, incidence of gout is not uniform. In a survey ( by me ) out of 34 batches involving a total of 1,05,990 chicks, gout was seen in 15 ( 44%) batches. In 11 of these, treatment was effective and total mortality due to gout remained restricted to around 2.%. However in the remaining four batches, treatment was refractory and mortality reached 10 to 29%.
5) Treatment and prevention :- Diuretics ( Lasix , Potassium chlorate ); anti-gout drugs ( Allupurinol ) and some propriety preparations have been used ( I have also used) but in nearly 25% out breaks, response to treatment is poor. In my use, I have found GOUTEX ( Guybro) has an edge over others and hence it is in my prescription
6) Strategy for prevention and treatment of Gout in commercial broilers:-
I have been using following strategy :-
i) Stop using prestarter feed In first week, use starter + 10 to 12% additional methionine , Lysine and Vit ADECK preparation.
ii) During 0 to 3 Weeks --- provide more space, ventilation + 10% additional waterers +cool drinking water + proper brooding.
iii) Use good quality Toxin binders , Acidifiers( they reduce gout) and antioxidants in all feed.
B ) Preventive Gout treatment from 5 to 12 day age
a) 8% Jaggery water in morning only + Goutex 10ml/100 chicks /day
C ) In the event of high uncontrolled mortality due to gout:-
Feed 50% + 50% Crushed maize containg all medicine and mineral pack
+ jaggery water as above + Goutex 15ml/100 chicks per day
till mortality shows downward trend ( generally in 2 to 3 days ).
Dr V.S.Narsapur ( 14/05/2011 )