Discussion created on 05/27/2020

Effect of citric acid on live vaccine

Respected Srs, greetings. I have high water PH in my farm and I used citric acid as acidifier to reduce the PH .Has the acidified water by citric acid any effect on live vaccine that sometimes I used .

Anonymous query
Saudi Arabia
Biologist
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Dr.Mujahid Kamran Dr.Mujahid Kamran
DVM MSC Microbiology
May 28, 2020
Hi yes acidic water effects live vaccines quality therefore when use vaccine in D/W PH range should be 6.5-6.8.
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Kasame Trakullerswilai Kasame Trakullerswilai
Bacheler of Veterinary Medicine
May 29, 2020
mixed with some neutralizer may be better and cool water be used,
or individual vaccinate
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Dr. Rama Prasad Chakraborty Dr. Rama Prasad Chakraborty
Specialist in Animal Nutrition
May 29, 2020
It is prefered to bring the PH absolutely neutral under chilled state at 4° C ,no matter what you add to that media being used prior vaccination. Hence during vaccination use acid or alkali free water or else the same could affect the true efficacy of such live vaccine.
Dr.R.P.Chakraborty
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Badal Singh Badal Singh
veterinary science
May 31, 2020
first what is the normal Ph of water at your farm...?
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Anonymous query
Saudi Arabia
Biologist
June 1, 2020
Badal Singh
8
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Badal Singh Badal Singh
veterinary science
June 22, 2020
Salah Mohammed dear during live vaccine dont used any chemical used some neutralizer only
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Asok Kumar Asok Kumar
Ph.D (veterinary Pathology)
July 23, 2020
Always stop acidifier use during any vaccine application by water....
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Fred Hoerr
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