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Antibiotics Alternatives: the multiple effects of butyrate.

Published on: 05/18/2017
Author/s : Haitham Yakout, PhD - Nutriad

Throughout the human history, utilization of antimicrobials in food production and human health have been greatly favored. Tremendous improvement in farm animal production and historically unprecedented enhancement in human health protection were marked benefits of utilizing antibiotic in agricultural and human medical arenas. However, the misuse and overdose of antibiotics has resulted in acceler...

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May 18, 2017
Christopher Hettiarachchi Sri Lanka

Well written article and results have been presented in an striking manner, particularly Fig. 2. PDCB can be a good alternative to water administered organic acids. Dr. Yakout, thank you for the informative article.
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May 18, 2017
Very good information on the various positive effect of Butyric acid in the gut. The concept is really good for prevention of NE in poultry. Though Butyric acid has no direct effect on Clostridium but can help indirectly by keeping a healthy gut.
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Atef Abou Zead Atef Abou Zead
professor of viral poultry diseases
May 18, 2017
Very informative article.
But . What are the different uses in poultry between :
1-the butyric acid and salts of butyric as sodium butyrate?
2-The capsulated butyric acid and non capsulated ?
Reply
Philippe Gossart Philippe Gossart
Consultant
May 18, 2017
Thank you ... for the long list of actions and effects of sodium butyrate (and not butyric acid which will not have the effectiveness of sodium Butyrate, acid will be unable to arrive in the intestin, the site of action) ... It would be honest also to add that only the form Butyrate Not dissociated arrival in the intestine will be able to this long generic results ... It is all too easy to take advantage of the literature and benefits of Butyrate...when it is added 50% or 70% stearin (antinutritional) !!! Which radically changes its efficiency capabilities...and more on young animals with immature digestive equipment !!!
Under the name Butyrate ... many products do their marketing, but very few products are able to satisfy the major goals of sodium Butyrate and their especially users ... what are screaming in the comparative tests ...

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Sataluri Satagopa Raja Ayyangar Sataluri Satagopa Raja Ayyangar
B .Sc ( Mathematics , Physics and Chemistry ) ; P G Diploma in Environmental Studies ; P G Diploma in Industrial Pollution Management ; Industrial Chemistry ( B I E T )
May 22, 2017

There are so many herbals and plants which can counter Antibiotics. Only the thing is they are to be made public and informative.There is separate Aurveda in India in which you can find the data. Our forefathers kept all the information for universal usage without any commercial benefit.

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Alabi Kehinde Alabi Kehinde
Animal Nutritionist
May 22, 2017

This is informative. More work should be done on this to reduce the risk of antibiotic resistance in our livestock.

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Yusuf Konca Yusuf Konca
Full Professor
May 23, 2017

Now we are studying on two separate experiments with capsulated butyric acid (Sodium butyrate) in older laying hens and layer chicks (from 0 to 30 weeks).

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Dr.Muhammad Khalid Qureshi Dr.Muhammad Khalid Qureshi
Animal Nutritionist
May 23, 2017

You have given good information about Butyrate, I would appreciate still more information.

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Babar Hilal Abbasi Babar Hilal Abbasi
Agro Engineer Zootechnist
June 2, 2017

Yes, it is time to minimize the use of antibiotic as an AGP and any alternative for this is required because in Asia, and especially in Pakistan, the poultry production is still on old methodology and the birds remain challenged from the pathogenic microorganism.

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June 6, 2017
Thank for the informative article. For greater synergy a combination of different organic acids with varying molecular weights brings best result. Consider combining with salts of formic, proprionic, acetic and or butryric/lactic/citrate acid will create a strong antimicrobial activity while improving the gut health hence performance.
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Tu HO Tu HO
Executive
June 15, 2017

As AGPs replacement. It is very good to have actiscles with full information like theirs to have a full understanding about agps'replacement. Which one should be the best choice for agps replacements?

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