Breakthrough in the Limitation of Probiotic Pelleting for Poultry and Livestock

As the global animal husbandry industry enters the post-antibiotic era, “gut microbiota” replacing antibiotics has become the current new topic of discussion in animal intestinal nutrition. There are over 400 different microbial organisms in the animal intestinal tract, which can be classified into pathogenic, neutral and beneficial bacteria, that influencing the physiological functions, for instance, digestive, metabolic, immunomodulation and energy conversion, etc. Lactic acid bacteria are the largest group of beneficial bacteria, and it is considered as probiotics to have a close symbiotic relationship with the host.

Lactic acid bacteria in general terms are the bacteria which can break down carbohydrates and produce more than 50% lactic acid. Additionally, it can produce organic acids, hydrogen peroxide, ethylene, bacteriostatic substances and others to inhibit the pathogenic bacteria. The mechanisms such as competitive exclusion and antagonistic activity are similar to the antibiotics in disease prevention, which allow further reductions of the disease rate, and therefore enable the host to spend less energy combating against disease and use for growing. This is also one of the most important reasons for probiotics to replace antibiotics. Take poultry as example, many reports have pointed out that the probiotics can improve chicken weight gain, FCR, mortality rate, and egg production.

The reasons why the outcomes of probiotic products fed to animals are not consistent may be related to the property of the strain, the screening and manufacturing process of the strains, and the timing of use, etc. SYNLAC™ products are developed under SYNTEK™ thorough system with SYNBIO TECH INC. unique Culture Collection and Data Bank. The strains are selected and isolated from the health animal intestinal tract or natural environments. We success to develop the branded SYNLAC™ product in animals based on the physiological criteria, for instance, Lactobacillus plantarum LP28 and Enterococcus faecium EF08 have properties of high intestinal adhesion, pathogen inhibition, assisting in immune regulation and promoting a synergistic effect among other strains. Lactobacillus acidophilus LAP5 can prevent livestock from diarrhea. Bacillus subtilis can secrete multiple enzymes to breakdown large molecular compounds.

SYNLAC™ is suitable for use in poultry drinking system, powdered and pelleted feed. Under high temperature manufacturing processes, SYNLAC™ stains are formed a postbiotic combination, exhibiting functions from both live and killed bacteria. When animals ingest the feed into their gastrointestinal tract, live bacteria can colonize on the intestinal villi, and secrete bacteriocin, lactic acid, and other antimicrobial substances that enable to balance the microflora in the intestinal tract. Additionally, it promotes the turnover of villi growth and crypt cell and enhances the nutrition absorption. On the other hand, the bacterial cell wall fragments produced by the high-pressure heat-killed increases the contact surface area with the intestinal villi. Moreover, the released bacterial cytoplasm and nucleic acid components can be delivered to the Payer’s patch via M cells to bind with immune cells, promoting the different cytokines of production for immune cell growth or conversions such as IL-10, IFN-γ, and others. These can boost the organism’s immune system against disease, reduce the probability of inflammation, and reduce energy wastage.

For more information, please contact us. You are welcome to come and visit us at the IPPE 2019, Atlanta, Ga. Feb. 12-14, 2019. Hall A, Stand 744, and VIV Asia 2019 Expo, Hall 105 Stand 1044, Bangkok, Thailand, March 13-15.