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Dietary tributyrin, an HDAC inhibitor, promotes muscle growth through enhanced terminal differentiation of satellite cells

Published: July 10, 2019
Summary
Introduction Postnatal muscle growth and repair rely on the ability of satellite cells, muscle-resident stem cells, to activate, proliferate, and fuse into growing myofibers (Seale et al. 2000; Dumont et al. 2015). During the neonatal stage of life, the fractional rate of protein synthesis contributing to muscle growth is highest (Davis and Fiorotto 2009), marked by increased satellite cell ac...
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Authors:
Chad H. Stahl
University of Maryland (USA)
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Juarez Donzele
Universidade Federal de Viçosa - UFV
25 de julio de 2019

Dr. Chad, great article. With reference to their information, it can be deduced that the microbiota, due to the production of volatile fatty acids, including butyric, directly influences the health and development of pigs. Thus, it is evident that one of the desired characteristics in the strains of microorganisms that are used as probiotics is their ability to promote increased butyric acid production.

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