Mycotoxin and Gut Microbiota Interactions

Published on: 5/28/2021
Author/s : Life Rainbow Biotech

Mycotoxins are secondary metabolites produced by fungi, the most abundant of which belong to the genera Aspergillus, Penicillium, and Fusarium. Acute exposure to high doses is usually responsible for well-characterized diseases, while sub-chronic and chronic exposure to low doses have been less well characterized but are considered as being responsible for reduced performance, for the reduced ability of the organism to defend itself against pathogens, and more generally for many of the causes of damaged heath.

Because mycotoxins are mainly present in food and feed, the gut is the first target for mycotoxin toxicity, but it is also the site of the absorption of mycotoxins that leads to systemic exposure to these compounds. The first, which concerns the effects of the gut microbiota on mycotoxins, is the ability of the microbiome to modify the toxicity of mycotoxins. For example, ruminant species can decrease in toxicity in most cases, but in monogastric species only can acid hydrolysis of some conjugates. The small intestine of all species microbiote-hydrolysis of conjugates and increase in toxicity in most cases. (Figure 1).

Life Rainbow Biotech has 15 years of research on mycotoxins and has developed new type detoxify mycotoxin product, mycotoxin degrading enzymes-Toxi-Free PLUS®, consists of three different type enzymes in one product which specific activity to convert mycotoxins into nontoxic to reduce the toxicity caused to animals.

Toxi-free PLUS® is specially designed feed additives to protect animals' health by counteracting mycotoxins through multiple strategies, which including mycotoxin degrading enzymes, selected-absorbent and herb extract ,proven to be effective and specific in farm trial and scientific trial.

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