What was the performance of the cows?

We in Israel use 16.2-16.7 % CP depending on MUN looking to achieve 12-16 MUN flat TMR the entiere lactation as roughage is very expensive.
We do not use ruman protected amino acids but the TMR is much more diverce in protien feedstufs than the Wisconsin diet. We use soy, canola, DDGS, sunflower mill as protein sources, so we are not sure that the Mepron or AminoShure-XM can help improve nitrogen efficiency.

Methionine has many metabolic roles, so it is not just protein in milk. In any case if you are interested in raising your milk protein you have to consider also the metabolizable Lysine, the rapport between metabolizable Lys and metabolizable Met and the quantity of metabolizable Lys & Met /Mcal ME.

A rough guideline would be a % over total metabolizable protein of 6,8-7% Lys and 2.40-2,70% Met (depending if your aim is % of protein in milk or milk yield), but it is as important or more to supply 1,17 gr metabolizable Met/Mcal ME and 3,15gr metabolizable Lys/Mcal ME

Dear Shahzaib Shakeel, thanks for your question.
It is essential to calculate the amino acid supplementation on the basis of the metabolizable methionine or lysine content.
The mMet content of Mepron is 612g/kg. If we used another product with the same mMet content, we supplemented the same grams of that product as we used Mepron and got the same result.
With products lower in mMet content than Mepron, the grams per day need to be higher to supplement equal grams of mMet to achieve the same results.
In addition to mMet content, physical resistance against mechanical stress is important. Due to its strong coating, Mepron often outperformed competition products on the same mMet supply level.
Regards,
Claudia