Use of Toxin Binders in livestock industry: a review

Congratulations for the timely article. Very few livestock producer give such importance to the quality of feed animal as we are concious to our own feed.
Animal productivity is directly dependent on keeping the animal health. mycotoxins present in animal feed is never taken seriously specially in third world. Mycotoxins are more active in animal feed as this food is not cooked and it is erved as it is.
This article will help creating awareness among livestock producers which will ultimately be in the benefit of farmers

Cholestyramine (CSM) has been shown in multiple studies to provide significant benefit to reduce symptoms and inflammatory markers in people exposed to interior environments of water-damaged buildings. Other toxin-binders, like activatded charcoal and bentonite clays, do not provide such benefit. The hypothesis is that CSM binds to toxins and inflammagens, interrupting the entero-hepatic recirculation. Do we know if dietary sources of mycotoxins can result in inflammatory changes from innate imunity (pro-inflamamtory cytokines, TGF beta-1 and C4a, for example) in animals? If so, does that mean we could be seeing entero-hepatic recirculation of mycotoxins from feed?
Ritch Shoemaker MD
Pocomoke Md
USA

Thanks for information about the Use of Toxin Binders in livestock industry.

Good article.Under primary mechanism through which mycotoxins affect animals,the details given are the symptoms and not the mechanism.These symptoms are because of action on different systems.

The biggest issue about mycotoxins is there presence in milk. The level of mycotoxins in feed directly influence its level in the milk posing a serious threat to the health of children. Maize and rice bran are the biggest culprit. If maize is replaced with wheat in animal feed then the level of aflatoxin in milk was with in permissible limit. The toxin binder also helps in reducing the level in milk. More reasearch is needed for the effect of toxin binder on the absorption of nutrients especially minerals.

Mycotoxins are critical in tropical countries, as the hot and humid climate encourage the production of mycotoxins. Immune-suppressed birds due to mycotoxins would not develop immunity following vaccination therefore remain susceptible to common viral infections like ND and IBDV or bacterial infection like E.Coli.

mycotoxin has been a serious headache of farmers in tropical region basically due to high temperature and humidity. the lower inclusion rate of this products makes it a good choice in africa. kindly give me further details about the product -prices, minimum quantity and other requirement to become your representative in Nigeria

Mycotoxins are matter of great concern in tropical countries for animals as well as for human beings. Several scientific studies have confirmed that mycotoxins residue is found in milk which is a threat to public health.

This article will help create awareness & understand benefit to dairy farmers to increase their farm production and consequently avoid public health hazards.

Overall a good article!

Very instructive article. Hight level of mycotoxins in feed is big problem in some of CIS countries. In this mater, Aflabond TM ( Montajat Vet.Pharmaceuticals ) have been recently used successfully in some swine farms in Belarus.

In the store where feeds are kept, only binders has been used successfully. But I need clarifications on which is the best? Charcoal or honey which can be able to protect the birds from toxins that are presents in the feed when ingested into the GIT of the animals precisely briolers?

How can a feed be formulated without toxins present in the feed already? That is no value for binders in the livestock industry.