Poultry research translates to vaccine development

Published: February 20, 2014

Source : PHRN

The road from research to application and development can be long, but Dr. Eva Nagy is nearing a milestone in her work in veterinary virology as she works with Mexico-based vaccine company, Avimex Animal Health, on poultry vaccine development. There are no Canadian poultry vaccine manufacturers.

Nagy and her research team are using a strain of fowl adenovirus, FAdV-9, a strain that doesn’t cause disease in poultry, as a vaccine vector for recombinant virus vaccine.

The biological platform went to Avimex in 2010, but they are now at the stage they are confident it will be a success, says Nagy. This platform will have many applications for many different avian viruses, such as Newcastle disease virus, avian influenza virus, infectious bronchitis virus, and even for bacteria.

“The significance of the FAdV-9 system is that we can generate multivalent vaccines and very importantly it allows us to differentiate infected from vaccinated animals (DIVA),” adds Nagy.

At present, Avimex is working on the registration of FAdV-9 and scaling up production.

Nagy also provided a second platform, FAdV-4, to Avimex more recently. Vaccine development with this platform is not as fully developed.

Nagy worked on the licensing process for FAdV-9 and FAdV-4 with the University of Guelph’s Catalyst Centre.

Funding for Nagy’s work was provided by the Canadian Poultry Research Council in partnership with Agriculture and Agri-Food Canada, the Natural Sciences and Engineering Research Council and OMAF.

Nagy is a member of the Poultry Health Research Network, which was recently launched at the University of Guelph. Network researchers work collaboratively to find solutions to a wide-range of poultry issues and offer expertise in a wide range of areas, from virology and vaccine development and disease modelling, to field-level issues that affect flock health and welfare such as parasite management and caging systems and lighting in barns.

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Maheswar Rath

11 de abril de 2014

this article is just a promotion activities of the center. Do this information send any massage? Of course it is good to see that this organization is involved for developing vaccines for poultry diseases even polyvalant vaccines of any poultry disease. I wish this centre for all success to come up with good scientific vaccines for development of poultry all over the world. thank you . dr m rath

Abdelseed Ahmed

9 de abril de 2014

As discussed above Nagy is promising the poultry producers with an excellent opportunity to solve health problems regarding poultry diseases . We in Sudan are facing a wide range of poultry health problems. The innovation of combined vaccines should be one of the most promising solutions and still it is not widely applied in Sudan . We hope Nagy will succeed but still we need to know more about this new product , the bacterial recombinants that should be included in the vector virus , efficency and the immunity level that can be reached .