Pathogenesis of avian pathogenic E. coli (APEC)
Forum: Recent Insights into APEC Pathogenesis and Control
Published on: 06/07/2012
Author/s : Lisa K. Nolan, DVM, PhD (Iowa State University), Catherine M. Logue, PhD, MIFST
THE ROLE OF PLASMIDS IN APEC´S BASIC BIOLOGY
We have found that large plasmids (extrachromosomal ´accessory´ DNA present in some bacteria) are a defining trait of the APEC pathotype, occurring in ~80% of APEC and harboring many of the genes thought to be linked to APEC´s abilities to cause disease and resist therapy. Such plasmids are often transmissible to recipient bacte...