Dear Munawar Ali,

Congratulations for the article about Coccidiosis in poultry. It really demonstrates the importance of the water as same ingredient, many times forgotten.

Mathews

Dear friend,

I finished placing commentary of one another article published here.

But I want to give to the congratulations for the boarded form in this article in relation  Coccidiosis in poultry problem that affects as many farms and that, the times, well is not decided with the additive inclusion in the diets.

Mathews

Live vaccines can have problems with safety, short shelf-life and large-scale production therefore there is continued interest in devising new vaccines using defined recombinant antigens.

Problems also noted with strain-specific immunity therefore a cocktail of antigens from different coccidial strains may be required.

Improving our knowledge of the coccidial transmission routes, host-coccidia relationships, coccidial pathogenesis and determining the various roles of the host immune response being at times host-protective, coccidia protective and in causing immunopathology will help to tailor a vaccination strategy against a particular coccidiosis in poultry target.

Very informative article about coccidiosis in poultry with brief description of mechanism of action of both classes of anticoccidials, inophores and chemicals.

Thank you the coccidiosis in poultry is important diseses which is caused great financial losses to the poultry industry and now adays in my country the most one is acervullena

Best Regards

Dear Dr Amit Raj Gupta, Thank you for your informative article. Your correctly mention the problem concerning the survival of drug-resistant strains of coccidia. I’d like to notify readers of a feed additive which has interesting properties against this particular pathogen to the extent that in some countries it is being used as a method of effective control against coccidiosis.

Based on essential oils, Orego-Stim® is able to break the lifecycle of Eimeria, not just in one or a couple of species as is the case with some anticoccidiostats, but in all species of Eimeria due to its’ unique mode of action on all lengths of the gastro intestinal tract. Orego-Stim® is also able to counter secondary invading bacterial diseases such as Clostridium perfringens, the causative agent of necrotic enteritis.

The phenolic compounds present in the essential oils act on the enterocytes adjacent to the lumen of the intestinal tract by increasing the rate of turnover of these cells from 4-7 days to 2-4 days, consequently interupting the lifecyle of Eimeria species. The sporozoite-infected cells are shed before development of the merozoite stage, which prevents the main clinical signs of coccidiosis. Due to this unique mode of action, resistance is unable to develop and there is no withdrawl period because it is a 100% natural product.

Orego-Stim® also encourages the build up of immunity against coccidiosis by allowing small amounts of oocysts to complete their lifecycle. This activates the Bursa-derived cell-mediated immunity, releasing macrophages, lymphocytes and natural killer cells to provide a longer-lasting immunity against this problematic disease.

THANKS FOR VERY CONSOLIDARED INFORMATION ABOUT  COCCIDIOSIS IN POULTRY

Thank you for this excellent pedagogic presentation Coccidiosis in poultry is a disease that is cosmopolitan, causing economic losses. Only prevention can reduce morbidity and mortality (hygiene, coccidiostats, immunization). Vaccination is the best way to limit the infection, but it comes very expensive, especially for farmers in developing countries. Vaccination is not economical for broiler chickens, however it would be very useful for reproducer breedings and laying hens.

Nice article to understand the life cycle of coccidiosis and use of anicocidial,chemiclas & ionophores to solve the disease causing heavy loss to poultry.

Good article about  coccidiosis in poultry. For use in our medicine.