New techniques and sampling tools among the conclusions of the 9th World Mycotoxin Forum
Published: July 19, 2016
Source : www.bastiaanse-communication.com/wmfmeetsiupac
At the conclusion of the 9th World Mycotoxin Forum and the 14th IUPAC International Symposium on Mycotoxins -that took place last June at Winnipeg, Canada-, this were the main lessons learned, as explained by General Conference Chairs Rudolf Krska and Hans van Egmond, and the session chairs.
1st lesson: We are living in a changing world
• Changing world = changing technology, changing mycotoxin patterns, diverse dietary patterns...
• Climate change and extreme weather conditions – old problems become new ones (ergot in W-Canada).
• Large collaborative projects have been launched with increasing involvement of Asia and Africa.
• Food authorities/international organisations: from reactive to proactive approaches.
• Economic & human health costs can be equated but the methods for assessment are arbitrary.
2nd lesson: We need to consider co-exposure to multiple mycotoxins & other contaminants
• Recent mycotoxin surveys prove co-occurence of multiple mycotoxins including modified forms.
• Food authorities recognise mycotoxin co-occurrence as a priority in exposure assessment.
• in vitro models still prevail, challenges to move to in vivo models for risk assessment.
• New technologies (HCA) assist in assessing combined effects of various food contaminants.
• Different modes of action are a major challenge for toxicological evaluation.
3rd lesson: New advanced tools for sampling and analysis
• On-line FAO sampling tool to visualize effects of sampling plan parameters on risk of mischaracterizing commodity lots.
• Advanced MS methods lead to a clearer picture on the range of occurring (masked) fungal secondary metabolites (e.g. in barley).
• New approaches for biomarker analysis (including blood spot analysis) provide new insights into the exposure to mycotoxins, their metabolism and the efficacy of detoxifiers.
• Omics technologies are becoming an important data source for:
- improved risk assessment.
- understanding plant-fungi interactions as a basis for sustainable prevention strategies.
4th lesson: Success stories and new promising techniques
• Biocontrol: expanding application of AflasafeTM atoxigenic Aspergillus technology in Africa has dramatically reduced aflatoxin contamination of maize.
• Using novel compounds including natural products inhibit toxin production in the plant and mitigate the physiological impact on intestinal tissue.
• Use of hyperspectral imaging or NIRT as noninvasive analytical techniques e.g. for sorting.
• Clear trend towards ICT based tools including novel handheld devices, provision of on-line data via apps.
5th lesson: Need for integrated approaches
• Going beyond field-to-fork: new approaches consider the entire cycle incl. waste management, alternative energy - within multi-actor efforts.
• Importance of the understanding of the fungi´s lifecycle and its interaction with host & environment.
• Post-harvest techniques incl. novel milling, thermal processing and detoxification techniques become increasingly attractive to minimize the mycotoxin content.
• Regulations to be effective to avoid adverse health effects have to impact the whole chain.
Source
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22 de julio de 2016
Yes, I am agree with this. And every time that in the younger most of Broiler breeder, broiler chicken and layer flock, the immunosuppression disorder from both of mycotoxins and unproperly nutritional (nutrional deficiency) are very serious.
In Thailand year 2016, we have both of Aflatoxin and some of Fusariotoxins like Fumonisin, DON and DAS were affected to our production. Induce breaking of MD and IBD again.
Dr. Damnern Sohsuebngarm
DVM & MSci. of Avian Medicin, PHD student.
21 de julio de 2016
with a great respect to the mentioned lessons in new techniques and sampling tools of Mycotoxines that play a very important and critical role in poultry industry , in my point of view for the the threat of mycotoxines in vaccination failure in poultry operations especially in vaccine against some pathogens for example MDV as the infectivity of the virus retained for 8 months at room temp. in birds feather and dander and also ILT that retain latent in trigeminal ganglia for up to 60 days in addition to the most of viruses that given as live attenuated vaccine were able for shedding for up to 10 days post vaccination .
in this period as the birds were laden with viruses, mycotoxines in the ration exhaust the immune system and can result in immunosuppression this in turn initiate this latent pathogens to proliferate and can induce outbreak in addition to the insufficient specific and effective immune defense to be achieved, this need further concern about the critical role of mycotoxines as immunosuppression and their impact on vaccine efficacy.
Abeer shahin
Avian Diseases
Vet. Med. Zagazig, Egypt
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