All clays means, Colloidal clay, HSCAS, Bentonite...Among these, which is better? What are the other clays available globally for mycotoxin control?Is there any interrelation between gut Ph & on the action of these clays? Is there any detoxifying agent instead of binders?
Dear Dr. Tamames, I would like to comment your part about being careful with biotransformation of mycotoxins… Up to now a lot of research has been done to adsorb or deactivate mycotoxins in feed with products that can be mixed into the feed and work directly inside the GIT of the animal. While the use of products based on aluminosilicates gave good results in counteracting aflatoxins, the adsorptive deactivation of other toxins - mainly trichothecenes (non-adsorbable), failed. Especially hydrated sodium alumino silicates (HSCAS) have been extensively studied because of their promising aflatoxin- binding capacity. Although HSCAS were demonstrated to be very effective with regard to preventing aflatoxicosis, their efficacy against zearalenone and ochratoxin A is limited and in the case of trichothecenes, it is practically zero (Ramos et al., 1996). Biotransformation, which is proved by long term research and supported by several scientific publications, involves a very specific chemical reaction which is changing mycotoxin into non-toxic metabolite in irreversible and safe way. Very intensive research (in vitro and in vivo) in the field of biotransformation is a warranty that this methods of mycotoxin deactivation are working in optimal and sub-optimal GIT conditions in presence or not presence of antibiotics, acidifiers, phytogenics, probiotics etc.