TECHNICAL ARTICLES - FEED MACHINERY
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The utilization of MOS, or yeast cell walls, has gained momentum in animal nutrition, and their efficacy is now well recognized. Consequently, it has become difficult to distinguish between a growing number of products on offer, of uneven quality and composition. As a yeast producer, Lallemand has initiated a reflection on the subject which resulted in a set of simple criteria aimed at evaluating the quality of MOS products. Based on these guidelines, we have been able to optimize our production and purification process in order to offer a MOS with optimal and consistent quality, which will guarantee its efficacy.
Yeast derivatives are gaining momentum in animal nutrition. They have become a well accepted ingredient for several reasons:
Yeast cell walls are now used in most animal species with various alleged effects, from immune stimulation (for β-glucans) to the control of digestive balance and limitation of the colonization of the digestive tract by pathogenic bacteria (for Manno-Oligosaccharides -MOS-), through to the binding and elimination of toxins present in certain cereals.
The recognition of yeast cell walls efficacy in animal nutrition has given rise to the multiplication of offers, in particular products commonly described as "MOS". Consequently, it has become difficult to distinguish between a wealth of products on offer, of uneven quality and composition.
Since the efficacy of an ingredient is directly linked to its composition, quality should always be a key issue. This applies to yeast cell walls, since their efficacy in animals is linked to the activity of the Manno-Oligosaccharides and β-glucans particles. However, yeast cell walls structure and composition are closely linked to the yeast fermentation conditions (temperature, pH, nutrients...) as well as to the type of yeast strain used. Bearing this in mind, it seems that the quality and composition of "MOS" issued from yeast autolysates or by-products of the brewery and distillery industries of inconsistent quality and origin is questionable. This issue is all the more important at a time when ingredients' origin and composition must be precisely stated. The recent detection of antibiotic residues (monensin) in yeast cell walls products derived from distillery by-products is a call for better transparency concerning the composition and origin of this type of ingredients.
Based on this statement and Lallemand's long-standing expertise of yeast biology and production, we drew a checklist of simple and objective criteria in order to define an optimal MOS product whose quality and homogeneity should be guaranteed (see boxed text). Based on our latest technological development in yeast cell walls extraction and purification process, we have developed and optimized AGRIMOS®, a MOS product of consistent high quality for optimal efficacy.
AGRIMOS® is a combination of purified Mannan-oligosaccharides (MOS) and ß-glucans for animal nutrition applications. Agrimos manufacturing process has been designed specifically, and each step of the production process, from the petri dish to the pure yeast cell wall, is tightly controlled.
Two main characteristics differentiate AGRIMOS from other "MOS" products on the market:
AGRIMOS is a suitable solution to help improve performance in terrestrial and aquatic farmed animals, to help prevent and reduce the risks of pathogens infections and help animals weakened by stress or intense growth. Thanks to the latest technological development in MOS production processes, we can now offer farmers an effective solution whose quality and homogeneity is guaranteed.
Truthfull to its commitment to support its products with expertise and technical advices, Lallemand offers feed the tools to assess themselves the quality of MOS ingredients available thanks to a set of objective criteria
* yeast cells grown specifically in order to extract their different fractions (cell walls, cytoplasmic content...).
Guidelines to evaluate the quality of MOS products1. Consider the origin and manufacturing process of the product. Consistent and high quality MOS is obtained from a specific and unique primary * yeast culture grown under well defined and monitored conditions. Products obtained from distillery and/or brewery by-products show: - lower quality levels, - important variations in terms of composition due to the use of by-products of variable and unknown quality, - risk of contamination because of the uncertainty about the origin of the by-products. Ex: antibotics. 2. Know how to interpret the product composition Protein concentration is a good indicator of the degree of purity of the product. The lowest the protein content, the more effective the separation process between the extract and the cell wall. Consistent and traceable quality is a major criterion guaranteeing efficacy. - Mannans and ß-Glucans contents should be systematically measured and guaranteed. - Standard deviation for each active substance must be indicated. - Methods of analysis must be provided. 3. Check the physical aspect of the product - A light cream color and a typical yeast smell are signs of a well purified product. - The low size and the uniformity of the particles highly increase product efficacy. - The solubility of the product in water is an easy criteria to assess the level of purification. A low solubility is a sign of purity.
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